Topics to be learn :
- Living organisms and life processes.
- Living organisms and energy production.
- Some nutrients and energy efficiency.
- Cell division - A life process.
Functions of Food Stuffs and Their Nutrients:
- Energy Source: Body needs continuous energy.
- Food Digestion: Food is digested into soluble nutrients.
- Nutrient Transport: Nutrients carried by blood to every cell.
- Oxygen Transport: Oxygen carried to every cell for respiration.
- Energy Production: Oxygen oxidizes nutrients in cells to produce energy.
- Body Functions: Energy helps body functions; nutrients aid growth and development.
Importance of Balanced Diet:
- Nutrient Proportions: Carbohydrates, proteins, fats, vitamins, and minerals in right proportions.
- Specific Functions: Each nutrient has specific functions.
- Health Maintenance: Balanced diet important for health.
Functions of Muscles in Body:
- Voluntary Muscles: Move according to will.
- Involuntary Muscles: Control vital activities; e.g., visceral organs.
- Cardiac Muscles: Control heart movements.
- Nutrient Storage: Carbohydrates and proteins stored in muscles.
Importance of Digestive Juices:
- Enzyme Presence: Digestive juices contain enzymes.
- Catalysts: Enzymes speed up chemical reactions.
- pH Regulation: Stomach juices make pH acidic; intestinal juices make it alkaline.
Excretory System: Waste Removal: Removes nitrogenous waste from body.
Circulatory System:
- Nutrient Transport: Glucose from digestive system, oxygen from respiratory system to every cell.
- Red Blood Cells: Carry oxygen; pumped by heart.
- Energy Production: Glucose oxidized in cells with oxygen.
Living Organisms and Life Processes:
- System Coordination: Different systems work together in living organisms.
- Homeostasis: Advanced in human body.
- Coordinated Systems: Digestive, respiratory, circulatory, excretory, nervous systems, and internal organs work together.
- Nutrient Transport: Circulatory system transports digested nutrients to cells.
- Energy Sources: Carbohydrates, fats, and lipids provide energy.
- Mitochondrial Role: Mitochondria synthesize energy from nutrients in cell cytoplasm.
- Importance of Oxygen: Oxygen is essential for energy production.
- Nutrient and Oxygen Transport: Circulatory system transports nutrients and oxygen to cells.
- Nervous System Control: Controls actions, maintaining life, and aiding growth and development.
Plants' Life Processes:
- Autotrophic Nature: Synthesize own food via photosynthesis.
- Food Storage: Stored in fruits, roots, stem-tubers, leaves, etc.
- Human and Animal Nutrition: Obtain nutrients from plants.
Carbohydrates:
- Sources: Milk, fruits, jaggery, cane sugar, cereals, vegetables, potatoes, sweet potatoes, sweetmeats.
- Functions: Provide 4 Kcal energy per gram.
Respiration:
- Release of Energy: From assimilated food.
- Breathing: Inhalation and exhalation.
- Gas Exchange: Oxygen in, carbon dioxide out.
- External Respiration: Oxygen to blood, CO2 out through alveolar membrane.
- Internal Respiration: Oxygen to cells, energy produced in mitochondria.
- Energy Form: ATP produced by oxidation of nutrients.
Living Organism and Energy Production:
- Body Level Respiration: Exchange of oxygen and carbon dioxide with surroundings.
- Cellular Level Respiration: Oxidation of foodstuffs in cells.
Cellular Level Respiration:
- Dietary Carbohydrates: Used for ATP production.
- Oxidation of Glucose: Step-by-step process.
- Two Methods: Aerobic (with oxygen) and Anaerobic (without oxygen).
Aerobic Respiration:
Glycolysis:
- Glucose oxidized into pyruvic acid, ATP, NADH, water.
- Takes place in cytoplasm.
- Pyruvic acid converted to Acetyl-CoA, NADH2, CO2.
Tricarboxylic Acid Cycle (TCA):
- Acetyl-Co-A enters mitochondria.
- Acetyl part oxidized, releasing CO2, H2O, NADH2, FADH2.
Electron Transfer Chain (ETC):
- Occurs in mitochondria.
- NADH2, FADH2 participate.
- NADH2 produces 3 ATP, FADH2 produces 2 ATP.
- ATP and water produced.
Coenzymes in Cellular Respiration:
- NADH2: Nicotinamide Adenine Dinucleotide.
- FADH2: Flavin Adenine Dinucleotide.
- Formed in cells, participate in respiration.
Utilization of Lipids and Proteins:
- Lipids: Converted to fatty acids, then Acetyl-Co-A.
- Proteins: Broken down to amino acids, then Acetyl-Co-A.
- Acetyl-Co-A undergoes complete oxidation via Krebs cycle for energy release.
ATP (Adenosine Triphosphate):
- Energy Storage: Energy stored in phosphate bonds.
- Cellular Storage: Stored in cells as needed.
- Chemical Composition: Adenosine ribonucleoside, containing adenine, ribose, three phosphate groups.
- Energy Currency: ATP breaks phosphate bond to release energy, known as 'energy currency' of the cell.
Glucose Molecule:
- Chemical Formula: C₆H₁₂O₆.
- Covalent Bonds: Hold atoms together.
- Oxidation: Gain oxygen atoms, lose electrons during oxidation.
Cellular Processes and Their Researchers:
- Glycolysis: Discovered by Gustav Embden, Otto Meyerhof, Jacob Parnas.
- Also known as Embden-Meyerhof-Parnas (EMP) pathway.
- Tricarboxylic Acid Cycle: Discovered by Sir Hans Krebs.
- Also called Krebs cycle.
Aerobic Respiration Process:
- Energy Production: Aerobic respiration of carbohydrates, proteins, and fats.
- Anaerobic Respiration: In living organisms/cells.
- Some bacteria and lower organisms cannot survive in the presence of oxygen.
- They perform anaerobic respiration for energy.
- Anaerobic respiration has two steps: Glycolysis and fermentation.
- Glycolysis: Glucose incompletely oxidized, releasing less energy.
- Fermentation: Pyruvic acid converted to organic acids or alcohol (C₂H₅OH).
- Process: Aided by enzymes.
- When oxygen levels are low:
- Higher plants, animals, and aerobic microorganisms may also perform anaerobic respiration.
- Examples:
- Submerged Soil: Seeds undergo anaerobic respiration during germination.
- Exercise: Human muscle cells switch to anaerobic respiration.
- Result: Less energy released, lactic acid accumulation leads to fatigue.
Energy from Different Food Components:
Carbohydrates: Excess stored as glycogen in liver and muscles.
Proteins:
- Structure: Formed by amino acids held by peptide bonds.
- Digestion: Converted back to amino acids.
- Absorption: Amino acids absorbed into blood, transported to cells.
- First Class Proteins: Animal proteins.
- Energy: 4 Kcal/g.
- Excess Intake: Broken down into ammonia, eliminated from body.
- Gluconeogenesis: Excess proteins converted to glucose.
- Plants: Produce amino acids from minerals.
Lipids:
- Components: Fatty acids and glycerol.
- Digestion: Converted to fatty acids and glycerol.
- Function: Produce various substances in cells.
- Examples: Phospholipids (plasma membrane), hormones, nerve cell coverings.
- Storage: Adipose tissue.
- Energy: 9 Kcal/g.
Vitamins:
- Function: Essential for body functioning and maintenance.
- Types: Fat soluble (A, D, E, K), Water soluble (B, C).
- Specific Functions: Riboflavin (Vitamin B2) - production of FADH2, Nicotinamide (Vitamin B5) - production of NADH2.
Water:
- Essential Nutrient: Crucial for body function.
- Body Composition: 66-70% water, 70% in every cell, 90% in blood plasma.
- Importance: Dehydration affects cell and body function.
Cell Division: An Essential Life Process
Introduction:
- After Injury: Cells and tissues can't function immediately.
- Injury Response: Blood capillaries rupture, inflammation occurs, damaged cells.
- Healing Process: Scab forms, surrounding cells divide rapidly to restore lost cells.
- Plant Sensations: Recent discoveries show plants also regenerate lost tissues through cell division.
Growth of Living Organisms:
- Cell Increase: Living organisms grow with an increase in cell number.
- Regular Cell Division: New cells added regularly for growth.
- Essential for Growth: Cell division necessary for body growth, tissue regeneration, and repair.
Reproduction:
- Asexual Reproduction: Involves mitosis for forming new individuals.
- Sexual Reproduction: Gametes formed by meiosis (reduction division), Chromosomes, genes, DNA ensure similarity with existing species.
Significance of Cell Division:
- New Organism Formation: From existing one.
- Growth of Multicellular Organisms: Essential for growth.
- Tissue Restoration: Injured or emaciated body can be restored.
Types of Cell Division: 1. Mitosis & 2. Meiosis
(i) Mitosis:
Stages: Karyokinesis: Nuclear division, Cytokinesis: Cytoplasmic division.
Karyokinesis:
(a) Prophase:
- Chromosome condensation starts.
- Chromosomes thicken, seen as sister chromatid pairs.
- Centrioles duplicate, move to opposite poles.
- Nuclear membrane and nucleolus disappear.
(b) Metaphase:
- Chromosomes condense fully.
- Each with sister chromatids.
- Align at equatorial plane.
- Spindle fibers attach to centromeres.
- Nuclear membrane disappears.
(c) Anaphase:
- Centromeres divide.
- Sister chromatids separate.
- Pulled to opposite poles by spindle fibers.
- Look like bunch of bananas.
(d) Telophase:
- Reverse of prophase.
- Chromosomes decondense.
- Nuclear membrane and nucleolus reappear.
- Spindle fibers lost.
- Cell appears to have two nuclei.
Cytokinesis:
- Notch develops in animal cell center.
- Deepens, cytoplasm divides.
- Plant cells: Cell plate forms, then divides.
Significance of Mitosis:
- Growth of body.
- Restoration of emaciated body.
- Wound healing.
- Blood cell formation.
(ii) Meiosis:
Stages: Meiosis I & Meiosis II
Meiosis I:
- Diploid cell forms four haploid cells.
- Crossing over occurs, genetic recombination.
- Daughter cells not identical.
- Forms spores and gametes.
- Maintains chromosome number.
(a) Meiosis I:
- Homologous chromosomes cross over.
- Divided into two groups, form two haploid cells.
- Prophase I subdivided into: Leptotene, Zygotene, Pachytene, Diplotene, Diakinesis.
- Similar to mitotic division.
- Haploid cells further divide, forming four haploid cells.
- Diploid (2n) vs. haploid (n).
- In '2n', chromosomes in pairs; in 'n', single chromosome of each type.
Important Features of Mitosis and Meiosis:
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